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Phosphatidylserine (PS) is directly or indirectly implicated in practically every cell membrane from the brain and nervous system to hormone function and the adrenal glands. Although an exhaustive list of possible applications for the phospholipid is not included, the following are the primary scientifically backed reasons why anyone – from children to post graduate doctoral candidates – should add PS from iStressedOut to their health, wellness and recovery regimen.

  1. PS enhanced mood in a group of young people during mental stress.[1]

  1. Children and young adults also get benefits in maintaining a sharp mind and controlling stress with PS.[2]

  1. Students experience improved learning abilities and performance.[3]

  1. Young university students experience significantly less stress from tests, stay more clear-headed and composed, and keep a more stable mood when taking PS.[4] 

  1.  PS helps your brain cells to metabolize glucose, to release and bind with neurotransmitters, all of which is important to learning, memory and other cognitive functions.

  1. PS restores the brain's supply and output of acetylcholine, the neurotransmitter so important to memory.[5]

  1. Patients diagnosed with clinical depression have shown marked improvement in their symptoms as a result of taking PS daily.[6],[7]

  1. PS helps insomnia and sleep disorders caused by excess cortisol at the end of the day.[8]

  1. Diets are deficient in PS and Modern industrial food production of fats and oils decreases all of the natural phospholipids—including phosphatidylserine.[9]

PS is an essential brain and memory supplement for students of all ages.

Chew 1 iStressedOut tab 3 times a day.



[1] Jäger R, Purpura M, Geiss KR, Weiß M, Baumeister J, Amatulli F, Schröder L, Herwegen H. (12 2007). "The effect of phosphatidylserine on golf performance". Journal of the International Society of Sports Nutrition 4(1): 23. doi:10.1186/1550-2783-4-23. PMC 2217563. PMID 18053194

[2] Benton D et al. The influence of phosphatidyl serine supplementation on mood and heart rate when faced with an acute stressor. Nutr Neurosci 2001;4(3):169-78.

[3] Ibid.

[4] Ibid.

[5] M.G.Vannucchi, F. Casamenti, G. Pepeu.Decrease of acetylcholine release from cortical slices in aged rats: investigations into its reversal by Phosphatidylserine. J.Neurochem 1990, 55, 819-25.

[6] von Zerssen D, Doerr P, Emrich HM, Lund R, Pirke KM. Diurnal variation of mood and the Cortisol rhythm in depression and normal states of mind. Eur Arch Psychiat Neurol Sci. 1987;237:36-45.

[7] Kennedy SH, Tighe S, McVey G, Brown GM. Melatonin and Cortisol "switches" during mania, depression, and euthymia in a drug-free bipolar patient. Am J Psychiatry 1998 Aug; 155(8):1119-21

[8] Journal of Clinical Endocrinology & Metabolism August 2001; 86:3787-3794

[9] M. Hamm. Ernährungswissenschaftliche Stellungnahme zur Veränderung der nutritiven Versorgung mit Phosphatidylserin (PS), 2002.

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